Bioengineering

Bioengineering is an emerging branch of engineering that primarily deals with problems of medicine, healthcare, and—in genera—quality of human life. It is a multidisciplinary field that combines scientific principles of biology, chemistry, physics, and mathematics with the best engineering techniques developed in traditional areas (for example, mechanical, electrical, chemical, and computer engineering) and new breakthrough methods developed in recent years.

Activities of bioengineers are widely spread. They use their knowledge to design and build medical instruments, artificial organs, prosthetic limbs, therapeutic devices, and medical imaging equipment. They help doctors to design new medical procedures, including new rehabilitation techniques. They also assist pharmaceutical and biotechnology industries in developing new, more efficient bioprocessing technologies. Finally, they find solutions for medical and biology-related problems of consumer technology in the areas of safety, ergonomics, and comfort.

Bioengineering is a rapidly growing profession with expanding career opportunities. By virtue of their vigorous cross-training, bioengineers are well-poised for careers in healthcare, medical device production, pharmaceutical industries, and consulting in health-related fields, as well as other positions in industry, education, and government.

Undergraduate Degree Program

The undergraduate program in bioengineering provides first a strong foundation in all of the basic ingredients of engineering: the natural and physical sciences, mathematics, a comprehensive socio-economic-cultural background, the behavioral sciences, and finally the basic engineering sciences that begin the development of problem-solving skills.

The program integrates natural sciences with engineering analysis and design concepts to advance the fundamental understanding of biological systems and to develop biology-based technologies with applications across a wide spectrum of societal needs. The bioengineering curriculum is designed to cater to students looking to enter the professional world immediately after earning their undergraduate degree, as well as those who are interested in pursuing graduate studies and research. Various fundamental, design, and application oriented courses (e.g. Biomaterials, Biomechanics, Bioinstrumentation, Biotransport, and Bioprocesses) fulfill industrial needs and help students to perform well in biotech, pharmaceutical, and healthcare industries as engineering professionals. At the same time, the exposure to advanced courses and cross-cutting, state-of-the-art research experiences provide a solid foundation to continue graduate studies and emerge as leaders in science and engineering.

Program Educational Objectives

The Program Educational Objectives for the Bachelor of Science in Engineering in Bioengineering are:

  1. Be successfully employed in their discipline or closely related field and contribute to the economy and healthcare.
  2. Graduates continue to enhance their knowledge base and skills through graduate or other professional development, to keep abreast of ongoing changes in technology and health-related disciplines.
  3. Graduates be well rounded and well suited to work with colleagues and professionals with diverse technical backgrounds and cultures and a wide range of competencies including those related to healthcare.

To achieve the educational objectives, the graduates of the program will have:

  1. an ability to apply knowledge of mathematics, sciences and engineering.
  2. an ability to design and conduct experiments, as well as to analyze and interpret data.
  3. an ability to design a system, component or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety,manufacturability, and sustainability.
  4. an ability to function on multidisciplinary teams.
  5. an ability to identify, formulate and solve engineering problems.
  6. an understanding of professional and ethical responsibility.
  7. an ability to communicate effectively.
  8. the broad education necessary to understand the impact of engineering solutions in a global economic, environmental, and societal context.
  9. a recognition of the need for, and an ability to, engage in life-long learning.
  10. a knowledge of contemporary issues.
  11. an ability to use the techniques, skills and modern engineering tools which are necessary for engineering practice.

Concentration Requirements

A candidate for the degree Bachelor of Science in Engineering (Bioengineering) is required to pursue scholastic quality and to complete satisfactorily the following program of study:

Bioengineering Program for Students Admitted as Freshmen1

(128 hours)

Dearborn Discovery Core Requirement

The minimum passing grade for a Dearborn Discovery Core (DDC) course is 2.0. The minimum GPA for the program is 2.0. In addition, the DDC permits any approved course to satisfy up to three credit hours within three different categories. Please see the General Education Program: The Dearborn Discovery Core section for additional information.

Foundational Studies

Written and Oral Communication (GEWO) – 6 Credits

Upper Level Writing Intensive (GEWI) – 3 Credits

Quantitative Thinking and Problem Solving (GEQT) – 3 Credits

Critical and Creative Thinking (GECC) – 3 Credits

Areas of Inquiry

Natural Science (GENS) – 7 Credits

  • Lecture/Lab Science Course
  • Additional Science Course

Social and Behavioral Analysis (GESB) – 9 Credits

Humanities and the Arts (GEHA) – 6 Credits

Intersections (GEIN) – 6 Credits

Capstone

Capstone (GECE) – 3 Credits

In addition to completion of the Dearborn Discovery Core, the following courses are required to earn a BSE degree in Bioengineering from UM-Dearborn. 

Basic Preparation for Engineering
CHEM 134
CHEM 136
General Chemistry IA
and General Chemistry IIA
8
MATH 115Calculus I4
MATH 116Calculus II4
MATH 205Calc III for Engin Students3
or MATH 215 Calculus III
MATH 216Intro to Diff Equations3
MATH 217Intro to Matrix Algebra2
or MATH 227 Introduction to Linear Algebra
BIOL 103Anatomy and Physiology I4
BIOL 140Intro Molec & Cellular Biology4
General Physics I, II8
ENGR 100Intro to Eng and Computers2
ENGR 126Engineering Computer Graphics2
ENGR 216Computer Meth for Engineers2
ENGR 250Principles of Eng Materials3
ME 230Thermodynamics4
ME 265Applied Mechanics4
ECE 305Intro to Electrical Eng4
Professional Subjects and Program Electives
BENG 325Thermofluid for Bioengineering4
BENG 351Bio-Sensors & Instrumentation4
BENG 370Biomechanics I4
BENG 364Prob&Stat in Bioengineering3
BENG 375Biomaterial Tissue Engrg4
BENG 381Bioprocessing4
BENG 4671Senior Design4
Bioengineering Design and Electives
Select 19 credits of Design or Upper-Level Tech Elective courses from lists below. At least one course must be a Design Course (3 or 4 credits)19
Select one Design Course:
Fundamentals of Drug Delivery
Microfluidics
Nanobiosystems Engineering
Biomechanics II
Biomimetics
Six Sigma & Stat Proc Improv
Human Factors and Ergonomics
Des and Analy of Mach Elem
Directed Design Project
Upper-Level Tech Electives:
Principles of Biochemistry
Bioinformatics
Transport in Biosystems
Regenerative Eng
Guided Study in Bioengineering
Organic Chemistry I
Organic Chemistry II
Organic Chemistry Laboratory
Nano-Biotechnology
Nanoscience and Nanotechnology
Eng Economy and Dec Anlys
Industrial Robots
Finite Element Method wth Appl
Control Syst Anly and Design
Directed Research Problems
Total Credit Hours107
1

Information for students planning to transfer to UM-Dearborn from community colleges or from four-year colleges and universities is given under Admission Information in the General Information section and under Undergraduate Requirements in the Engineering section of this Catalog.

BENG 325     Thermofluid for Bioengineering     4 Credit Hours

This course is an introduction into mass and heat transport phenomena in biomedical systems. Basic mechanisms of fluid flow, heat transfer, and diffusion are presented and applied to biological objects (cells, tissues, organisms) and biomedical devices. Topics include mass, momentum, and energy conservation laws, physical properties of common and biological fluids, elements of fluid statics, control volume analysis, basics of fluid mechanics, conduction and convection heat transfer, diffusion, applications to hyper- and hypothermia, thermal ablation, and cryopreservation, basics of mass and heat transfer in the body.

Prerequisite(s): ENGR 216 and ME 230 and (ME 265 or ME 345)

Restriction(s):
Can enroll if Class is Sophomore or Junior or Senior
Can enroll if College is Engineering and Computer Science

BENG 351     Bio-Sensors & Instrumentation     4 Credit Hours

The course covers measurements in biological materials using a variety of sensor technologies along with electronic instrumentation design and use. Safety and FDA requirements are also presented.

Prerequisite(s): ECE 305 and (ENGR 216 or ECE 270) and MATH 216 and BIOL 103 and BIOL 140

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if College is Engineering and Computer Science or Arts, Sciences, and Letters

BENG 364     Prob&Stat in Bioengineering     3 Credit Hours

Set theory, combinatorial analysis, probability and axioms, random variables, continuous and discrete distribution functions, expectations, Chebyshev?s inequity, weak law of large numbers, central limit theorem, sampling statistics and distributions, point and interval estimation, and linear regression.

Prerequisite(s): MATH 116 or MATH 114 or MPLS with a score of 215

Restriction(s):
Can enroll if Class is Sophomore or Junior or Senior
Can enroll if College is Engineering and Computer Science

BENG 370     Biomechanics I     4 Credit Hours

The course provides a basic understanding of how the human body functions as a mechanical system. Review of mechanics. Musculoskeletal anatomy, statics and kinematics, muscle force redundancy, joint mechanics. Bone and soft tissue mechanics, muscle active force generation. Implant stress shielding and impact safety. Laboratory experiments directed at rehabilitation engineering, biological bone and tissue property measurement, bone and implant structural analysis, and impact safety.

Prerequisite(s): (ME 265 or ME 345) and MATH 216

Restriction(s):
Can enroll if Class is Sophomore or Junior or Senior
Can enroll if College is Engineering and Computer Science or Arts, Sciences, and Letters

BENG 375     Biomaterial Tissue Engrg     4 Credit Hours

The course provides a basic understanding of the structure, properties and therapeutic applications of biomaterials, as well as the opportunities and scientific and technological challenges of tissue engineering. It also provides an integrated and multidisciplinary biological-engineering approach and probes mechanisms and methods of evaluation of tissue/biomaterials and patient/device interactions. Further the course assesses current outcomes, current challenges and cutting edge technological solutions to medical problems, Laboratory topics include key biological concepts, clinical safety, tissue culture, biological cells/bioactive materials interaction, and scaffold testing.

Prerequisite(s): ENGR 250 and BIOL 140

Restriction(s):
Can enroll if Class is Sophomore or Junior or Senior
Can enroll if Level is Undergraduate

BENG 381     Bioprocessing     4 Credit Hours

This course will introduce the students to the field of bioprocessing where the engineering concepts are applied to convert raw materials to pharmaceuticals, chemicals and food using biological processes. Discussions will include application of bioprocess-engineering knowledge in designing, building, controlling, and operating the biologically driven processes. Typical applications include bioreactor design, material collection and scale-up considerations. The course will also introduce the pharmacokinetics and pharmacodynamics analysis concepts to the students and will serve as an introductory course to teach how to use these concepts to design bioprocess-engineering systems. 4 credit hours (3 credit hours of lecture and 1 credit hour of lab).

Prerequisite(s): (ME 325 or BENG 325) and BIOL 140 and CHEM 136

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if Level is Undergraduate
Can enroll if College is Arts, Sciences, and Letters or Engineering and Computer Science

BENG 410     Bioinformatics     3 Credit Hours

This course covers fundamental computer skills for using various bioinformatics tools, querying bioinformatics databases, computational approaches and analysis methods for biological problems, and introduction to various programming languages and toolboxes for bioinformatics, data mining, and data visualization.

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if Level is Undergraduate
Can enroll if College is Arts, Sciences, and Letters or Engineering and Computer Science

BENG 425     Transport in Biosystems     3 Credit Hours

The course introduces transport phenomena in biological and medical systems to students already familiar with basic thermal-fluid sciences. Topics include properties of body fluids and cell membranes, blood flow and solute and oxygen transport in biological systems, basic principles of pharmacokinetic analysis, transport phenomena in medical devices and artificial organs.

Prerequisite(s): ME 375 or BENG 325

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if College is Engineering and Computer Science or Arts, Sciences, and Letters

BENG 426     Fundamentals of Drug Delivery     3 Credit Hours

This course is designed to provide students with an understanding on the concepts in drug delivery from an engineering perspective. The course will cover drug delivery mechanisms, quantitative understanding of drug transport, nanotechnology, drug delivery devices, toxicity and immune response, FDA regulations, clinical trials and technology transfer. The course will conclude with a design project on nanoparticles development for targeted drug delivery. (F)

Prerequisite(s): BENG 325 and BIOL 140

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if College is Arts, Sciences, and Letters or Engineering and Computer Science

BENG 451     Microfluidics     3 Credit Hours

Microscaled systems and devices have enhanced reaction rates, predictable fluidic mechanics, reduced reagent volumes, and also lowered cost of manufacturing. These advantages benefit many biomedical applications that require sensitive molecular detection in robust and economical devices. In this course, a range of microsystem techniques will be discussed, including those based on Microfluidics, BioMEMS, and Optofluidics. The lectures will meet twice a week, one hour each, and will be accompanied by student-driven design projects that will be conducted in 3-hour laboratories.

Prerequisite(s): (BENG 325 or ME 325) and (BENG 375 or BENG 381)

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if Level is Undergraduate
Can enroll if College is Engineering and Computer Science or Arts, Sciences, and Letters

BENG 460     Nanobiosystems Engineering     3 Credit Hours

Nanobiosystems Engineering is an emerging frontier in nanotechnology. It integrates materials science, bioengineering, physics and life science with the biological and biochemical applications. This fast-developing interdisciplinary field holds the promise to solve many of the medical problems of future. The course will introduce advanced concepts related to nanomaterials and nanofabrication and their application in medicine. The course will also focus on design and development of nano-devices for the applications of pharmaceuticals and healthcare. Typical applications include nano-biosensor, targeted drug delivery, and tissue engineering will also be discussed. Students in Bioengineering will have a chance to present and discuss individual application through team project.

Prerequisite(s): (ME 325 or BENG 325) or (ME 349 or BENG 351 and BENG 375)

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if Level is Undergraduate
Can enroll if College is Arts, Sciences, and Letters or Engineering and Computer Science

BENG 4671     Senior Design     4 Credit Hours

A guided design project course where student teams propose design projects, design a device, system or process related to bioengineering and conduct evaluative experiments and/or construct a physical prototype. Engineering ethics and responsibility. At the end of the semester, the students are required to submit written reports and give oral presentations with a demonstration of their projects

Prerequisite(s): BENG 325 and BENG 351 and BENG 364 and BENG 370 and BENG 375

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if Major is Bioengineering

BENG 470     Biomechanics II     3 Credit Hours

The course covers intermediate level subject matter on structural biomechanics. Topics include bone structure modeling, implant and fixation materials, analysis and design, ocular biomechanics, and head impact and injury.

Prerequisite(s): BENG 370

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if College is Arts, Sciences, and Letters or Engineering and Computer Science

BENG 475     Regenerative Eng     3 Credit Hours

This course will discuss principles of tissue engineering whereby the properties of stem as well as primary cells, growth factors, and extracellular matrix and their impact in the development of engineered tissue constructs will be explored. In addition, the course will also focus on supporting/enabling technologies typically utilized in engineering these constructs including nano- and micro-fabrication techniques, 3D printing, micro-patterning as well as designing principles of bioreactors, and drug and gene delivery techniques. Additionally, various tissue engineering applications will be discussed including synthetic tissues and organs that are currently under development for regenerative medicine application.

Prerequisite(s): BENG 370 and BENG 375

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if Level is Undergraduate
Can enroll if College is Engineering and Computer Science

BENG 481     Biomimetics     3 Credit Hours

The Biomimetic Engineering course will give an overview and in-depth analysis of nature?s solutions to specific problems with the aim of determining appropriate engineering analogs. Students will learn mechanical principles in nature and their application to engineering devices. Mechanical behavior of biological materials as governed by underlying microstructure will be discussed. Students will work in teams on projects where they will take examples of designs, concepts and models from biology and determine their potential in specific engineering applications. 3 credit hours

Prerequisite(s): (ME 325 or BENG 325) and (BENG 370 or ME 345)

Restriction(s):
Can enroll if Class is Junior or Senior
Can enroll if Level is Undergraduate
Can enroll if College is Arts, Sciences, and Letters or Engineering and Computer Science

BENG 490     Directed Design Project     1 to 3 Credit Hours

Design project involving not only design byt alson analysis, fabrication, and/or testing. Topics may be chosen from any of the areas of bioengineering. The student will need to submit a report on his or her project at the end of the term. (F, S, W)

Restriction(s):
Can enroll if Class is Senior
Can enroll if Level is Undergraduate
Can enroll if College is Engineering and Computer Science
Can enroll if Major is Bioengineering

BENG 492     Guided Study in Bioengineering     1 to 3 Credit Hours

Individual study, design, or laboratory research in a field of interest to the student. Topics may be chosen from any areas of Bioengineering. The student needs to submit a report on his or her project at the end of the term. (F, S, W)

Restriction(s):
Can enroll if Class is Senior
Can enroll if Level is Undergraduate
Can enroll if College is Engineering and Computer Science
Can enroll if Major is Bioengineering

 
*

An asterisk denotes that a course may be taken concurrently.

Frequency of Offering

The following abbreviations are used to denote the frequency of offering: (F) fall term; (W) winter term; (S) summer term; (F, W) fall and winter terms; (YR) once a year; (AY) alternating years; (OC) offered occasionally