Bioengineering

The Program

The master’s degree in bioengineering is a 30-credit-hour program designed to prepare students in an area of rapid growth and profound impact on society. The curriculum consists of courses specifically designed to provide a comprehensive background in the bioengineering field. Bioengineering courses are 3 credit hours and most are offered in the evening from 6:00 to 8:45 p.m.

The program may be completed entirely on campus, entirely online, or through a combination of on-campus and online courses.

Degree Requirements

The MSE in bioengineering is offered through the Horace H. Rackham School of Graduate Studies at the University of Michigan. The degree requirements for this program consist of a minimum of 30 graduate-level semester credit hours (beyond an undergraduate degree from an accredited engineering program) and includes 6 credit hours of core courses, 18 credit hours of bioengineering elective courses, and 6 credit hours of cognate elective courses.

Laboratory Facilities

The bioengineering laboratory is designed to provide students with hands-on experience in tissue engineering, biomechanics, and developing and characterizing biomaterials. The laboratory houses standard equipment and facilities required for biomaterial development, biomechanical testing, and tissue engineering. Equipment available for biomechanical testing includes eight axial test machines, a high rate tensile/compressive impact tester, a high speed imaging system, environmental chambers, and assorted fixtures.

Faculty

The BENG program faculty are engaged in research in orthopaedic biomechanics, human movement, ocular biomechanics, impact safety, biomaterials, tissue engineering, hypoxia, protein engineering, cellular engineering, biomineraliztion, biomimetics, biopreservation, bioprocessing, drug delivery, nanotheranostics, pharmaceutical formulation, microspectroscopy, thermogravimetrics, biophotonics, microoptics, biosensors, MEMS, and microfluidics.

Assistantships/Financial Assistance

Research assistantships may be available to exceptionally qualified students who are not otherwise employed. Tuition scholarships are available to qualified full-time graduate students. Find out more about bioengineering faculty and their research areas.

Core Courses

BENG 520Adv Molecular and Cell Biology3
ME 518Advanced Engineering Analysis3

Bioengineering Electives

2 courses (6 credit hours); select any 2 courses from the following list:
BENG 521Biomatis and Biochem Interface3
BENG 526Fundamentals of Drug Delivery3
BENG 550Biomed Optics and Biophotonics3
BENG 551Microfluidics3
BENG 560Nanobiosystems Engineering3
BENG 570Orthopedic Biomechanics3
BENG 571Impact Biomechanics3
BENG 575/ME 595Regenerative Engineering3
BENG 595Digital Manufacturing The student has the option of electing a thesis in lieu of 6 credit hours of coursework in the bioengineering electives area. 3
BENG 600Study or Research in BENG1-3

Cognate Electives

2 courses (6 credit hours); select any 2 courses from the following list:
BIOL 552Med & Env Toxicology3
BIOL 561Advances in Cell Biology2
CIS 515Computer Graphics3
CIS 551Advanced Computer Graphics3
ECE 552Fuzzy Systems3
ECE 554Embedded Systems3
ECE 554Embedded Systems3
ECE 560Modern Control Theory3
ECE 580Digital Signal Processing3
ECE 5831Pat Rec & Neural Netwks3
ECE 585Pattern Recognition3
IMSE 501Human Factors & Ergonomics3
IMSE 510Probability & Statistical Mod3
IMSE 511Design and Analysis of Exp3
IMSE 514Multivariate Statistics3
IMSE 543Industrial Ergonomics3
IMSE 544Industrial Biomechanics3
IMSE 545Vehicle Ergonomics I3
IMSE 546Safety Engineering3
IMSE 561Tot Qual Mgmt and Six Sigma3
IMSE 567Reliability Analysis3
MATH 504Dynamical Systems3
MATH 514Fin Diff Meth for Diff Equat3
MATH 516Fin Elemnt Meth for Diff Equat3
MATH 520Stochastic Processes3
MATH 523Linear Algebra w/Applications3
MATH 554Fourier and Boundary3
MATH 555Func of a Complex Var with App3
MATH 562Mathematical Modeling3
MATH 572Intro to Numerical Analysis3
MATH 573Matrix Computation3
ME 510Finite Element Methods3
ME 522Advanced Fluid Mechanics3
ME 525Computational Thermo-Fluids3
ME 540Mechanical Vibrations3
ME 542Advanced Dynamics3
ME 563Advanced Instrum and Control3
ME 571Conduction Heat Transfer3
ME 572Convection Heat Transfer3
STAT 530Applied Regression Analysis3
STAT 535Data Analysis and Modeling3
STAT 545Reliability & Survival Analys3
STAT 550Multivariate Stat Analysis3
STAT 560Time Series Analysis3

BENG 520     Adv Molecular and Cell Biology     3 Credit Hours

This course introduces the cell and molecular biology concepts from an engineering perspective and provides the foundation for modern biotechnology and bioengineering. This course is designed for a first year engineering graduate student to develop a comprehensive understanding of relevant applications in biology, including biochemical, cellular organizational, metabolic and genetics aspects. Advanced concepts including genomics, molecular biology, recombinant DNA technology and evolution are discussed. The course provides exposure to several key techniques used in biological engineering laboratories. Students will have chance to present and discuss individual application through team project. (YR)

Restriction(s):
Can enroll if Level is Rackham or Doctorate or Graduate

BENG 521     Biomatis and Biochem Interface     3 Credit Hours

The course will provide graduate-level foundation on biomaterials science and principles. Specifically, the course will involve discussion on the importance of surfaces and interfaces in biomaterial function and elements controlling host responses to materials, introduction to biomimetic and rational designing approaches, and develop critical analyses of biomaterials through reading research papers and developing projects. (YR)

Restriction(s):
Can enroll if Level is Graduate or Rackham or Doctorate

BENG 526     Fundamentals of Drug Delivery     3 Credit Hours

This course is designed to provide students with an understanding on the concepts in drug delivery from an engineering perspective. The course will cover drug delivery mechanisms, quantitative understanding of drug transport, nanotechnology, drug delivery devices, toxicity and immune response, FDA regulations, clinical trials and technology transfer. The course will conclude with a design project on nanoparticles development for targeted drug delivery. (YR)

Restriction(s):
Can enroll if Level is Doctorate or Rackham or Graduate

BENG 550     Biomed Optics and Biophotonics     3 Credit Hours

The recent explosion of interest in minimally invasive medical diagnostics has been fueled in part by the development of novel optics and photonics techniques and instrumentation designed specifically for medical applications. A large number of optically-based imaging and sensing diagnostics are now in use in both the research laboratory and medical clinic. Topics include engineering design principles of optical instrumentation for medical diagnostics, elastic and inelastic light scattering theory and biomedical applications, confocal and multiphoton microscopy, light propagation and optical tomographic imaging in biological tissues, and design of minimally invasive spectroscopic diagnostics. (YR)

Restriction(s):
Can enroll if Level is Rackham or Graduate or Doctorate

BENG 551     Microfluidics     3 Credit Hours

Microscaled systems and devices have enhanced reaction rates, predictable fluidic mechanics, reduced reagent volumes, and also lowered cost of manufacturing. These advantages benefit many biomedical applications that require sensitive molecular detection in robust and economical devices. In this course, a range of microsystem techniques will be discussed, including those based on Microfluidics, BioMEMS, and Optofluidics. The lectures will meet twice a week, one hour each, and will be accompanied by student-driven design projects that will be conducted in 3-hour laboratories. (YR)

Restriction(s):
Can enroll if Level is Rackham or Doctorate or Graduate

BENG 560     Nanobiosystems Engineering     3 Credit Hours

Nanobiosystems Engineering is an emerging frontier in nanotechnology. It integrates materials science, bioengineering, physics and life science with the biological and biochemical applications. This fast-developing interdisciplinary field holds the promise to solve many of the medical problems of future. The course will introduce advanced concepts related to nanomaterials and nanofabrication and their application in medicine. The course will also focus on design and development of nano-devices for the applications of pharmaceuticals and healthcare. Typcial applications including nano-biosensor, targeted drug delivery, and tissue engineering will also be discussed. Students in Bioengineering will have chance to present and discuss individual application through team project. (YR)

Restriction(s):
Can enroll if Level is Graduate or Doctorate or Rackham

BENG 570     Orthopedic Biomechanics     3 Credit Hours

This course applies the field of orthopedics to biomechanics. Structure and function of the musculoskeletal system in the intact and pathologic states will be reviewed. Further discussion will focus on the design of orthopedic implants for the spine and the appendicular skeleton. Biomechanical principles of fracture repair and joint reconstruction will also be addressed. (YR)

Restriction(s):
Can enroll if Level is Graduate or Doctorate or Rackham

BENG 571     Impact Biomechanics     3 Credit Hours

This course focuses on the understanding of the behavior of human organs, bone and tissue at their point of mechanical or functional failure. Topics will include research methods in injury biomechanics, injury tolerance of the structures and materials of the head, brain, spine, thorax, abdomen and extremities and injury prevention focusing on safety equipment. Federal motor vehicle safety standards will be discussed. (YR)

Restriction(s):
Can enroll if Level is Doctorate or Graduate or Rackham

BENG 575     Regenerative Engineering     3 Credit Hours

This course will discuss principles of tissue engineering whereby the properties of stem as well as primary cells, growth factors, and extracellular matrix and their impact in the development of engineered tissue constructs will be explored. In addition, the course will also focus on supporting/enabling technologies typically utilized in engineering these constructs including nano-and micro-fabrication techniques, 3D printing, micro-patterning as well designing principles of bioreactors, and drug and gene delivery techniques. Additionally, various tissue engineering applications will be discussed including synthetic tissues and organs that are currently under development for regenerative medicine application. (YR)

Restriction(s):
Can enroll if Level is Rackham or Doctorate or Graduate

BENG 595     Digital Manufacturing     3 Credit Hours

This combined lecture and hands on project course aims to train students to optimize the interplay of materials, people, machines and profitability. The course introduces methods to identify product concepts with commercial potential. Student teams will perform market analysis and explore the intellectual property space around their ideas and rapidly iterate them into a final prototype via direct digital manufacturing (e.g., 3D CAD/CAM files manifested via digital printing or machining). Advanced instruction on direct digital manufacturing tools will be given, and customer response will be used as feedback. Early stage prototypes will progress into more sophisticated designs, scaling up (cost, pricing, tooling, process flow and automation) scenario planning for mass manufacturing as well as Failure Mode Effect Analysis (FMEA) will be discussed. (W,YR)

Restriction(s):
Can enroll if Level is Graduate or Doctorate or Rackham
Can enroll if College is Engineering and Computer Science

BENG 600     Study or Research in BENG     1 to 3 Credit Hours

Individual study or research in an area of bioengineering under supervision of a faculty member. The student will submit a written report at the close of the term. (YR)

Restriction(s):
Can enroll if Level is Graduate or Doctorate or Rackham

BENG 699     Master's Thesis     1 to 6 Credit Hours

Research project in the area of bioengineering conducted under supervision of a program faculty member. While guided by a faculty member, a student electing this course is expected to carry out the work him-or herself. Successful completion of the course requires completion and public defense of a written thesis. A student must satisfactorily complete all 6 credit hours, which can be distributed over multiple semesters. (YR)

Restriction(s):
Can enroll if Level is Rackham or Graduate

 
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An asterisk denotes that a course may be taken concurrently.

Frequency of Offering

The following abbreviations are used to denote the frequency of offering: (F) fall term; (W) winter term; (S) summer term; (F, W) fall and winter terms; (YR) once a year; (AY) alternating years; (OC) offered occasionally