Bioengineering (BENG)

BENG 520     Adv Molecular and Cell Biology     3 Credit Hours

This course introduces the cell and molecular biology concepts from an engineering perspective and provides the foundation for modern biotechnology and bioengineering. This course is designed for a first year engineering graduate student to develop a comprehensive understanding of relevant applications in biology, including biochemical, cellular organizational, metabolic and genetics aspects. Advanced concepts including genomics, molecular biology, recombinant DNA technology and evolution are discussed. The course provides exposure to several key techniques used in biological engineering laboratories. Students will have chance to present and discuss individual application through team project. (YR)

Restriction(s):
Can enroll if Level is Rackham or Doctorate or Graduate

BENG 521     Biomatis and Biochem Interface     3 Credit Hours

The course will provide graduate-level foundation on biomaterials science and principles. Specifically, the course will involve discussion on the importance of surfaces and interfaces in biomaterial function and elements controlling host responses to materials, introduction to biomimetic and rational designing approaches, and develop critical analyses of biomaterials through reading research papers and developing projects. (YR)

Restriction(s):
Can enroll if Level is Graduate or Rackham or Doctorate

BENG 526     Fundamentals of Drug Delivery     3 Credit Hours

This course is designed to provide students with an understanding on the concepts in drug delivery from an engineering perspective. The course will cover drug delivery mechanisms, quantitative understanding of drug transport, nanotechnology, drug delivery devices, toxicity and immune response, FDA regulations, clinical trials and technology transfer. The course will conclude with a design project on nanoparticles development for targeted drug delivery. (YR)

Restriction(s):
Can enroll if Level is Doctorate or Rackham or Graduate

BENG 550     Biomed Optics and Biophotonics     3 Credit Hours

The recent explosion of interest in minimally invasive medical diagnostics has been fueled in part by the development of novel optics and photonics techniques and instrumentation designed specifically for medical applications. A large number of optically-based imaging and sensing diagnostics are now in use in both the research laboratory and medical clinic. Topics include engineering design principles of optical instrumentation for medical diagnostics, elastic and inelastic light scattering theory and biomedical applications, confocal and multiphoton microscopy, light propagation and optical tomographic imaging in biological tissues, and design of minimally invasive spectroscopic diagnostics. (YR)

Restriction(s):
Can enroll if Level is Rackham or Graduate or Doctorate

BENG 551     Microfluidics     3 Credit Hours

Microscaled systems and devices have enhanced reaction rates, predictable fluidic mechanics, reduced reagent volumes, and also lowered cost of manufacturing. These advantages benefit many biomedical applications that require sensitive molecular detection in robust and economical devices. In this course, a range of microsystem techniques will be discussed, including those based on Microfluidics, BioMEMS, and Optofluidics. The lectures will meet twice a week, one hour each, and will be accompanied by student-driven design projects that will be conducted in 3-hour laboratories. (YR)

Restriction(s):
Can enroll if Level is Rackham or Doctorate or Graduate

BENG 560     Nanobiosystems Engineering     3 Credit Hours

Nanobiosystems Engineering is an emerging frontier in nanotechnology. It integrates materials science, bioengineering, physics and life science with the biological and biochemical applications. This fast-developing interdisciplinary field holds the promise to solve many of the medical problems of future. The course will introduce advanced concepts related to nanomaterials and nanofabrication and their application in medicine. The course will also focus on design and development of nano-devices for the applications of pharmaceuticals and healthcare. Typcial applications including nano-biosensor, targeted drug delivery, and tissue engineering will also be discussed. Students in Bioengineering will have chance to present and discuss individual application through team project. (YR)

Restriction(s):
Can enroll if Level is Graduate or Doctorate or Rackham

BENG 570     Orthopedic Biomechanics     3 Credit Hours

This course applies the field of orthopedics to biomechanics. Structure and function of the musculoskeletal system in the intact and pathologic states will be reviewed. Further discussion will focus on the design of orthopedic implants for the spine and the appendicular skeleton. Biomechanical principles of fracture repair and joint reconstruction will also be addressed. (YR)

Restriction(s):
Can enroll if Level is Graduate or Doctorate or Rackham

BENG 571     Impact Biomechanics     3 Credit Hours

This course focuses on the understanding of the behavior of human organs, bone and tissue at their point of mechanical or functional failure. Topics will include research methods in injury biomechanics, injury tolerance of the structures and materials of the head, brain, spine, thorax, abdomen and extremities and injury prevention focusing on safety equipment. Federal motor vehicle safety standards will be discussed. (YR)

Restriction(s):
Can enroll if Level is Doctorate or Graduate or Rackham

BENG 575     Regenerative Engineering     3 Credit Hours

This course will discuss principles of tissue engineering whereby the properties of stem as well as primary cells, growth factors, and extracellular matrix and their impact in the development of engineered tissue constructs will be explored. In addition, the course will also focus on supporting/enabling technologies typically utilized in engineering these constructs including nano-and micro-fabrication techniques, 3D printing, micro-patterning as well designing principles of bioreactors, and drug and gene delivery techniques. Additionally, various tissue engineering applications will be discussed including synthetic tissues and organs that are currently under development for regenerative medicine application. (YR)

Restriction(s):
Can enroll if Level is Rackham or Doctorate or Graduate

BENG 595     Digital Manufacturing     3 Credit Hours

This combined lecture and hands on project course aims to train students to optimize the interplay of materials, people, machines and profitability. The course introduces methods to identify product concepts with commercial potential. Student teams will perform market analysis and explore the intellectual property space around their ideas and rapidly iterate them into a final prototype via direct digital manufacturing (e.g., 3D CAD/CAM files manifested via digital printing or machining). Advanced instruction on direct digital manufacturing tools will be given, and customer response will be used as feedback. Early stage prototypes will progress into more sophisticated designs, scaling up (cost, pricing, tooling, process flow and automation) scenario planning for mass manufacturing as well as Failure Mode Effect Analysis (FMEA) will be discussed. (W,YR)

Restriction(s):
Can enroll if Level is Graduate or Doctorate or Rackham
Can enroll if College is Engineering and Computer Science

BENG 600     Study or Research in BENG     1 to 3 Credit Hours

Individual study or research in an area of bioengineering under supervision of a faculty member. The student will submit a written report at the close of the term. (YR)

Restriction(s):
Can enroll if Level is Graduate or Doctorate or Rackham

BENG 699     Master's Thesis     1 to 6 Credit Hours

Research project in the area of bioengineering conducted under supervision of a program faculty member. While guided by a faculty member, a student electing this course is expected to carry out the work him-or herself. Successful completion of the course requires completion and public defense of a written thesis. A student must satisfactorily complete all 6 credit hours, which can be distributed over multiple semesters. (YR)

Restriction(s):
Can enroll if Level is Rackham or Graduate

 
*

An asterisk denotes that a course may be taken concurrently.

Frequency of Offering

The following abbreviations are used to denote the frequency of offering: (F) fall term; (W) winter term; (S) summer term; (F, W) fall and winter terms; (YR) once a year; (AY) alternating years; (OC) offered occasionally