Microbiology
Microbiology is the study of organisms that usually require the aid of a microscope in order to be seen.
Micro-organisms include viruses, bacteria, archaea bacteria, algae, fungi, and protozoa. Microbiologists seek to understand the interactions between these organisms and components of our biosphere. Many micro-organisms are essential for life, as we know it, to exist on earth. Many of these organisms produce useful biologically active products, such as enzymes and antibiotics. A small number of them cause diseases in plants and animals, including humans.
The study of micro-organisms has led to many important discoveries concerning:
- the complexities, universality and mechanism of expression of the genetic code;
- the transfer of genetic information between species and modulation of the gene pool;
- the mechanism of antigen-antibody reactions and cellular immunity;
- the synthesis of proteins, nucleic acids and other cellular constituents;
- the structure, function and biogenesis of membranes; and,
- the process of molecular and cellular differentiation.
Students majoring in Microbiology will understand basic principles relating to molecular, cellular and organismal biology. In addition to these, students will exhibit proficiency in selected empirical laboratory skills, develop knowledge of contemporary research using the scientific method and demonstrate competence in oral and written communication. This background of knowledge and experience will prepare the students for entry into professional/graduate school or for employment in government, academic or industrial positions. The learning goals are divided into five parts including (1) Conceptual knowledge; (2) Critical and independent thinking skills; (3) Communication skills; (4) Collaborative skills; and (5) Societal impact.
In addition to the major requirements, students must complete all CASL Degree Requirements.
Pre-Major Requirements
A solid background in mathematics is essential to success in any of the scientific disciplines. Incoming students who intend to choose a major in Microbiology should have completed at least three years of high school mathematics. First year students should plan to enroll in MATH 104 or MATH 105; MATH 113 or MATH 115; or MATH 114 or MATH 116 based on the results of their math placement tests. CHEM 134 or CHEM 144 and CHEM 136 or CHEM 146 are prerequisites to many other courses in the Natural Sciences Department; students majoring in any of the sciences should complete this sequence as soon as possible.
| Code | Title | Credit Hours |
|---|---|---|
| BIOL 130 & BIOL 140 | Intro Org and Environ Biology and Intro Molec & Cellular Biology | 8 |
| CHEM 134 | General Chemistry IA | 4 |
| or CHEM 144 | Gen Chemistry IB | |
| CHEM 136 | General Chemistry IIA | 4 |
| or CHEM 146 | General Chemistry IIB | |
| CHEM 225 & CHEM 226 & CHEM 227 | Organic Chemistry I and Organic Chemistry II and Organic Chemistry Laboratory | 8 |
| MATH 113 | Calc I for Biology & Life Sci | 4 |
| or MATH 115 | Calculus I | |
| Select one of the following: | 3-4 | |
| Calc II for Biology & Life Sci | ||
| Calculus II | ||
| Biostatistics I 4 | ||
| Statistical Computing 4 | ||
| Select one of the following: | 8 | |
| Introductory Physics I and Introductory Physics II (preferred sequence) | ||
| General Physics I and General Physics II | ||
| Total Credit Hours | 39-40 | |
Major Requirements
A minimum of 29 upper level credit hours in Microbiology (MICR) or Biological Sciences (BIOL) must be completed as outlined below:
Note: Students should begin the chemistry sequence before electing any MICR/BIOL course.
Required Courses
| Code | Title | Credit Hours |
|---|---|---|
| All of the following courses are required: | ||
| MICR/BIOL 385 | Microbiology | 4 |
| MICR/BIOL 405 | Applied & Environ Microbiology | 4 |
| MICR/BIOL 406 | Microbial Genetics | 3 |
| MICR/BIOL 440 | Micro Genetics & Physi Lab | 1 |
| MICR/BIOL 485 | Physiology of Microorganisms | 3 |
| Select at least one credit hour from the following: 1 | 1 | |
| Off-Campus Research | ||
| Seminar in Microbiology | ||
| Ind Study in Microbiology | ||
| Lab in Micro Research | ||
| Complete an additional 13 credit hours (to reach minimum 29 hours required for the major) from the following list, of which at least four credit hours must be from microbiology courses (MICR). | ||
| Microbiology (MICR) Courses- A minimum of 4 credit hours from: 2 | 4 | |
| Epidemiology | ||
| Topics in Microbiology 3 | ||
| Medical Virology | ||
| Virology | ||
| Immunology | ||
| Pathogenic Microbiology | ||
| Off-Campus Research | ||
| Seminar in Microbiology | ||
| Ind Study in Microbiology | ||
| Lab in Micro Research | ||
| Select a minimum of 9 credits from: | 9 | |
| Cell Biology | ||
| General Genetics | ||
| Histology | ||
| Principles of Biochemistry 5 | ||
| Epidemiology | ||
| Topics in Biology 3 | ||
| Medical Virology | ||
| Virology | ||
| Immunology | ||
| Pathogenic Microbiology | ||
| Biochemistry I 5 | ||
| Biochemistry II 5 | ||
| Biochemistry Lab I | ||
| Biochemistry Laboratory II | ||
| Molecular Biology | ||
| Seminar in Biology | ||
| Independent Study in Biology | ||
| Laboratory in Biological Resrh | ||
| Cognates | ||
| A minimum of six credit hours upper level courses from the following: | 6 | |
Any upper level courses in BCHM, CHEM, ENST, ESCI, GEOL, PHYS | ||
| Probability | ||
| Biostatistics I 4 | ||
| Statistical Computing 4 | ||
| Intro to Survey Sampling | ||
| Medical Ethics | ||
| Philosophy of Science | ||
| Medical Anthropology | ||
| Human Genetics | ||
| Physiological Psychology | ||
| Medical Sociology | ||
| Total Credit Hours | 35 | |
Other appropriate cognate courses may be permitted with approval of the faculty program advisor by petition.
| 1 | No more than a total of six credit hours combined in MICR 495, MICR 498, and MICR 499 may be applied toward the 120 credit hours required for graduation. Both MICR 498 and MICR 499 require independent study contracts agreed upon by a faculty member. |
| 2 | All 400-level MICR courses have MICR 385 as a prerequisite. |
| 3 | When topic is appropriate – must Petition. |
| 4 | STAT 301 or STAT 327 may be used as a pre-major requirement or as a cognate requirement but not both. |
| 5 | In the entire minimum 35 credit hours required for both the microbiology major and cognates, students may use either BIOL/BCHM/CHEM 370 or BIOL/BCHM/CHEM 470 and/or 471. |
Notes:
1. A maximum of 44 credit hours of MICR or BIOL may count in the 120 hours required for graduation.
2. At least 12 of the 29 credit hours of upper level MICR/BIOL used toward the major must be elected at UM-Dearborn.
3. A maximum of 6 credit hours of Independent Study (courses numbered 495, 498, 499) in any science discipline may count in the 120 hours to graduate.
4. A maximum of 6 credit hours combined in MICR 495/BIOL 495, MICR 498/BIOL 498, MICR 499/BIOL 499 may be applied toward the 29 credit hours required in the major.
5. In the entire minimum 35 credit hours required for both the microbiology major and cognates, students may use either BIOL/BCHM/CHEM 370 or BIOL/BCHM/CHEM 470 and/or 471.
6. Any one course may be used to satisfy only one requirement within the major.
Minor or Integrative Studies Concentration Requirements
A minor or concentration consists of 12 credit hours of upper-level courses in microbiology (MICR).
MICR 309 Introduction to Mycology 4 Credit Hours
An introduction to the biology of the fungi. Classification, structure, industrial use, gastronomic qualities, and disease-producing ability of macroscopic and microscopic forms are studied. Laboratories include microscopic and macroscopic examinations of fungi, and their growth and field studies on the occurrence and classification of edible and poisonous varieties. Three hours lecture, four hours laboratory. (OC).
MICR 380 Epidemiology 3 Credit Hours
Introduces the methods for infectious disease epidemiology (occurence and spread in population) and case studies of important disease syndromes and entities. Methods include definitions and nomenclature, outbreak investigations, disease surveillance, case-control studies, cohort studies, laboratory diagnosis, molecular epidemiology, dynamics of transmission, and assessment of vaccine field effectiveness. Case-studies focus on acute respiratory infections, diarrheal diseases, hepatitis, HIV, tuberculosis, sexually transmitted diseases, malaria and other vector-brone diseases. This course emphasizes methods of study that would contribute to understanding disease etiology.
Prerequisite(s): BIOL 140
MICR 385 Microbiology 4 Credit Hours
The biology of microorganisms is considered through study of the properties of bacteria, fungi, algae, protozoa, and viruses. Microbial structures are discussed and correlated with their function. Aspects of cellular metabolism pertinent to microorganisms are emphasized. The interaction of microorganisms and their environment, animate and inanimate, is discussed with respect to the beneficial or harmful effects of the different microbial groups. Laboratory exercises introduce the student to basic, practical microbiological techniques and illustrate various principles of microbial life. Three hours lecture, four hours laboratory. (F,S).
Prerequisite(s): BIOL 140 and (CHEM 134* or CHEM 144*)
Corequisite(s): MICR 385L
MICR 390 Topics in Microbiology 1 to 6 Credit Hours
Current topics in microbiology will be presented through a lecture, discussion and/or laboratory format. Topics will vary, as appropriate, and may cover any area of microbiology including studies on bacteria, algae, fungi, protozoa, viruses, biotechnology, mechanisms of pathogenesis and immunology. (OC).
MICR 405 Applied & Environ Microbiology 4 Credit Hours
Advanced treatment of the interplay of microorganisms and the environment. Topics will include soil and water microbiology (bacteria, archaea, fungi, algae, protozoans and viruses) and plant-microbe interactions (pathogenic and symbiotic) as well as the role of microorganisms in decomposition, nutrient cycling (carbon, nitrogen, sulfur and metal cycling), wastewater and biosolids treatment, and bioremediation. 3 hr lec, 1-4 hr lab. For graduate credit elect MICR 505.
Prerequisite(s): MICR 385 or BIOL 385
Restriction(s):
Can enroll if Class is Senior
MICR 406 Microbial Genetics 3 Credit Hours
A course that emphasizes the genetics and molecular biology of bacteria and their viruses. Topics include DNA structure and replication, recombination, DNA repair, genetic mapping, mechanisms of gene transfer, regulation of gene expression, mutagenesis, and recombinant DNA techniques. (YR, W).
MICR 430 Medical Virology 3 Credit Hours
The course provides a general description of the history and nature of animal virus disease. Emphasis is placed on the pathogenesis and clinical description of specific diseases. Three hours lecture.
MICR 440 Micro Genetics & Physi Lab 1 Credit Hour
This course emphasizes the use of advanced microbiological techniques for understanding the genetics and physiology of microorganisms. Experiments focus on the understanding of general microbial phenomena, such as nutrition, metabolism and biochemistry; protein and nucleic acid synthesis; energy generation, enzyme regulation, membrane transport, motility, differentiation, cellular communication and the behavior of populations.
Prerequisite(s): BIOL 385* or MICR 385* or BIOL 301* or BIOL 406* or MICR 406* or BIOL 485* or MICR 485*
Restriction(s):
Cannot enroll if Class is Freshman
Can enroll if Level is Undergraduate
MICR 450 Virology 4 Credit Hours
The first half of this course deals with bacterial viruses, with emphasis on classical events in this field. The second half surveys the field of animal viruses, with emphasis on recent discoveries, including replication, pathogenesis, and viral association with cancers. Three hours lecture, four hours laboratory. (AY,W).
MICR 455 Immunology 4 Credit Hours
A detailed study of the field of immunology. Among the topics covered are various aspects of the immunological response, such as humoral or cell-mediated immunity, cell-cell interactions, and immunology as related to the cause and prevention of disease. Three hours lecture, four hours laboratory. (AY,F).
MICR 459 Pathogenic Microbiology 4 Credit Hours
An introduction to pathogenic microorganisms and mechanisms of microbial pathogenicity. Disease-causing bacteria, fungi, viruses, and protozoa are studied. Laboratories emphasize clinical approaches to isolation, identification, and treatment. Three hours lecture, four hours laboratory. (AY,F).
MICR 485 Physiology of Microorganisms 3 Credit Hours
An in-depth examination of the physiology of microorganisms. Areas of emphasis include the growth and nutrition of microorganisms, the development of viruses, the microbial degradation of organic compounds, the regulation of degradation reactions, and the biosynthesis of uniquely microbial compounds and secondary metabolites, such as antibiotics and toxins. Consideration is given to the natural environments of specific microorganisms. (YR, W).
Prerequisite(s): (BIOL 385 or MICR 385 or BIOL 370 or CHEM 370 or BCHM 370) and CHEM 225*
MICR 495 Off-Campus Research 1 to 3 Credit Hours
Participation in ongoing experimental research at an off-campus laboratory (or in the field). Arrangements made between the research laboratory, (director of field study), the student, and the microbiology concentration advisor. No more than 6 hours combined from MICR 495, 498, and 499 may be credited toward the 120 hours required for a degree. Four to twelve hours laboratory. Permission of concentration advisor. (F,W,S).
MICR 497 Seminar in Microbiology 1 Credit Hour
Topics of current interest in microbiology will be presented by guest lecturers, faculty members or students. Topics chosen will vary from term to term. Can be elected up to three times. One hour seminar. Permission of instructor. (W).
MICR 498 Ind Study in Microbiology 1 to 3 Credit Hours
Library research and independent study performed under the guidance of a faculty member. Four to twelve hours readings. (F,W,S).
MICR 499 Lab in Micro Research 1 to 3 Credit Hours
Directed laboratory research performed under the guidance of a faculty member. Four to twelve hours laboratory. Permission of instructor. (F,W,S).
| * | An asterisk denotes that a course may be taken concurrently. |
Frequency of Offering
The following abbreviations are used to denote the frequency of offering: (F) fall term; (W) winter term; (S) summer term; (F, W) fall and winter terms; (YR) once a year; (AY) alternating years; (OC) offered occasionally